The NGS Core Facility together with I. Motorine (UMR7365 IMoPA) and M. Helm (Mainz university, Helm's lab) have organized a training school "NGS and Epitranscriptomics" in the frame of the COST Epitran (European Cooperation for Science and Technology) from 11th to 14th February 2019 in the Biopôle in Nancy.

This training in english was followed by 12 students (phD students and postdocs) and 4 young PIs coming from across Europe. During 4 days, participants have been initiated to practical as well as theoritical aspects of a new booming field : Epitranscriptomics. The participants have learned key concepts in different fields (molecular biology, next-generation sequencing and bioinformatics) allowing them to carry out a project to identify and quantify post-transcriptional modifications of RNA by high-throughput sequencing.

Four internationally renowned speakers have been invited to share and discuss their current research in this field :

• Pr Mark HELM (Johannes Gutenberg University, Mainz, Germany) : "Analysis of RNA modifications by LC-MS"
• Dr Jean-Yves ROIGNANT (Molecular Biology Institute, Mainz, Germany) : "RNA modifications and brain function"
• Pr Denis LAFONTAINE (Brussels University, Gosselies, Belgium) : "Eukaryotic ribosomal RNA modification, an overview"
• Dr Francesca TUORTO (DKFZ, Heidelberg, Germany) : "Detection of m5C in RNA by bisulfite sequencing”