Facility
Proteomics
Autoflex speed IV
Specificities :
- It is a mass spectrometer with MALDI ionization and linear and reflectron TOF analyzers including CID fragmentation chamber.
- The flight tube of the Autoflex IV in maintained under a vaccum in the 10-7 bar order to allow mass measurement precisions in the 10 ppm range.
- Most analyses performed on our mass spectrometer are fully automated and autonomous.
- The ionization source of our Autoflex IV is cleaned up manually on a weekly basis in order to maintain optimal sensitivity.
- Terms and conditions358.47 KB
This equipment is not available for booking. Please contact the Core Facility manager.
Henrionnet C, Gillet P, Mainard D, Vincourt JB, Pinzano A. Label-free relative quantification of secreted proteins as a non-invasive method for the quality control of chondrogenesis in bioengineered substitutes for cartilage repair. J Tissue Eng Regen Med. 2018 Mar ; 12(3):e1757-e1766.
10.1002/term.2454 , 
28485490 , 
HAL-01745215 Belcastro E, Wu W, Fries-Raeth I, Corti A, Pompella A, Leroy P, Lartaud I, Gaucher C. Oxidative stress enhances and modulates protein S-nitrosation in smooth muscle cells exposed to S-nitrosoglutathione. Nitric Oxide. 2017 Sep 30 ; 69:10-21.
10.1016/j.niox.2017.07.004 ,
28743484 Luo M, Boudier A, Pallotta A, Maincent P, Vincourt JB, Leroy P. Albumin as a carrier for NO delivery: preparation, physicochemical characterization, and interaction with gold nanoparticles. Drug Dev Ind Pharm. 2016 Dec ; 42(12):1928-1937.
10.1080/03639045.2016.1182546 ,
27126574 ,
HAL-01380405 Riffault M, Moulin D, Grossin L, Mainard D, Magdalou J, Vincourt JB. Label-free relative quantification applied to LC-MALDI acquisition for rapid analysis of chondrocyte secretion modulation. J Proteomics. 2015 Jan 30 ; 114:263-73.
10.1016/j.jprot.2014.10.026 ,
25464362 ,
HAL-01451913
