Bandeau PROTEO

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Biopôle

UMR7365 CNRS-Université de Lorraine
Ingénierie Moléculaire et Physiopathologie Articulaire (IMoPA)
Biopôle, Campus Brabois-Santé
9 Avenue de la Forêt de Haye, BP 20199
54505 VANDOEUVRE-LES-NANCY

jean-baptiste.vincourt [at] univ-lorraine.fr 03.72.74.66.82 French, English / UMR7365 IMoPA, Plateforme Protéomique

skills

  • Cellular Biology and Biochemistry
  • Mass spectrometry
  • Specialized in proteomics
  • Label-free relative quantification

Biography

Education

  • 2002 : PhD in Cellular and Molecular Biology, Institute of Pharmacology and Structural Biology (IPBS), University of Toulouse III.
  • 1999 : Master Thesis in Biochemistry and molecular biology, Microbiology and microbial genetics Laboratory (LMGM), University of Toulouse III.

 

Experiences

  • 2010-Present : Head of the Proteomics Core Facility at FR3209 and then at UMS2008 IBSLor
  • 2008-2010 : Research Engineer at CNRS, Articular Pharmacology, Physiopathology and Engineering (PPIA) Laboratory, Vandoeuvre-Lès-Nancy, France
  • 2005-2008 : Post-doc, Articular Pharmacology, Physiopathology and Engineering (PPIA) Laboratory, Vandoeuvre-Lès-Nancy, France
  • Sept 2004-Mai 2005 : Post-doc, mRNA localization and cell polarity Laboratory, Developmental Biology, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany
  • 2003-2004 : Post-doc, National Cancer Institute Experimental Immunology branch (NCI EIB), Bethesda, MD, USA.

Responsabilities

  • Head of Proteomics Core Facility
  • Expert in sample preparation and instrumental development
  • Expert in extracellular matrix chemical modification analysis

research

Current
Research

Mechanisms of collagen maturation

Key
Results

  • Henrionnet C, Gillet P, Mainard D, Vincourt JB, Pinzano A. Label-free relative quantification of secreted proteins as a non-invasive method for the quality control of chondrogenesis in bioengineered substitutes for cartilage repair. J Tissue Eng Regen Med. 2018 Mar;12(3):e1757-e1766. doi: 10.1002/term.2454.
  • Riffault M, Moulin D, Grossin L, Mainard D, Magdalou J, Vincourt JB. Label-free relative quantification applied to LC-MALDI acquisition for rapid analysis of chondrocyte secretion modulation. J Proteomics. 2015 Jan 30;114:263-73. doi: 10.1016/j.jprot.2014.10.026.
  • Bantsimba-Malanda C, Cottet J, Netter P, Dumas D, Mainard D, Magdalou J, Vincourt JB. Chondrocalcin is internalized by chondrocytes and triggers cartilage destruction via an interleukin-1β-dependent pathway. Matrix Biol. 2013 Oct-Nov;32(7-8):443-51. doi: 10.1016/j.matbio.2013.06.002.

Publications

teachings