LC-MALDI

Service overview

This service includes :

  • Chemical and enzymatic treatment of samples, being either polyacrylamide gel pieces or water-based solutions (with restrictions regarding buffer contents), for exhaustive identification of protein content.

  • NanoHPLC fractionation ; MALDI MS and MS/MS analysis ; database interrogation and analytical report.

classe plateforme
pf-proteomique

Access and Fees

  • If you are interested in this service, please contact the Core Facility manager to define the best strategy to adopt for conducting your study, and obtain a quote. Any user will agree to accept the terms and conditions.

Publications

  • Belcastro E, Wu W, Fries-Raeth I, Corti A, Pompella A, Leroy P, Lartaud I, Gaucher C. Oxidative stress enhances and modulates protein S-nitrosation in smooth muscle cells exposed to S-nitrosoglutathione. Nitric Oxide. 2017 Sep 30 ; 69:10-21.

    logo DOI - Digital Object Identifier 10.1016/j.niox.2017.07.004 , Logo PMID - PubMed 28743484
  • Luo M, Boudier A, Pallotta A, Maincent P, Vincourt JB, Leroy P. Albumin as a carrier for NO delivery: preparation, physicochemical characterization, and interaction with gold nanoparticles. Drug Dev Ind Pharm. 2016 Dec ; 42(12):1928-1937.

    logo DOI - Digital Object Identifier 10.1080/03639045.2016.1182546 , Logo PMID - PubMed 27126574 , logo HAL - Archives Ouvertes HAL-01380405