Facility
Biophysics & Structural Biology (B2S)
DSC
The microcalorimeter with temperature scanning (Microcal VP-DSC model) is mainly dedicated to the study of the thermal stability of macromolecules and their complexes. By measuring the variation of the heat capacity (ΔCp) as a function of the temperature (from -10 to 130 °C), the DSC allows the direct determination of the variations of enthalpy (ΔH) and entropy (ΔS), and the half-transition temperature (Tm) associated with each structural transition.
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Analyzes can be performed in service mode or device provision mode after initial training. Contact the person in charge using the Request form for any information.
Chagot ME, Boutilliat A, Kriznik A, Quinternet M. Structural Analysis of the Plasmodial Proteins ZNHIT3 and NUFIP1 Provides Insights into the Selectivity of a Conserved Interaction. Biochemistry. 2022 Mar 22.
10.1021/acs.biochem.1c00792 , 
35315277 , 
HAL-03617333 S Ahmed Zennia S, Mati A, Charron C, Cakir-Kiefer C, Kriznik A, Girardet JM. Effect of nonenzymatic deamidation on the structure stability of Camelus dromedarius alpha-lactalbumin.Food Chemistry. 2019 Avril 8.
10.1016/j.foodchem.2019.04.033 ,
HAL-02095313
