Facility
Biophysics & Structural Biology (B2S)
DLS
Dynamic Light Diffusion (DLS) allows to characterize the homogeneity of the solutions (monomodal or multimodal solution), the state of aggregation (mono- and poly-dispersity), the size of the particles (proteins, DNA-RNA, complex) by the estimation of the hydrodynamic radius (Rh), the stability of the macromolecules as a function of the temperature (increase of Rh) managed by the Peltier effect.
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Analyzes can be performed in service mode or device provision mode after initial training. Contact the person in charge using the Request form for any information.
Chagot ME, Boutilliat A, Kriznik A, Quinternet M. Structural Analysis of the Plasmodial Proteins ZNHIT3 and NUFIP1 Provides Insights into the Selectivity of a Conserved Interaction. Biochemistry. 2022 Mar 22.
10.1021/acs.biochem.1c00792 , 
35315277 , 
HAL-03617333 Beaussart A, Canonico F, Mazon H, Hidalgo J, Cianférani S, Le Cordier H, Kriznik A, Rahuel-Clermont S. Probing the mechanism of the peroxiredoxin decamer interaction with its reductase sulfiredoxin from the single molecule to the solution scale. Nanoscale Horiz. 2022 Mar 2.
10.1039/d2nh00037g ,
35234779 ,
HAL-03595966
